string ProtectPassword="111";
int ProtectLevel=3;  //3只填寫窗體，可參照列表對應，理論是1-4
 
/取得Word文件保存路徑
string _lastfile="";  //模板文件的路徑
            object filename = _lastfile;
            //創(chuàng)建一個名為WordApp的組件對象
            Word.Application WordApp = new Word.Application();
 
            //創(chuàng)建一個名為WordDoc的文檔對象
            WordApp.DisplayAlerts = Word.WdAlertLevel.wdAlertsNone;
           
            
            Word.Document WordDoc = WordApp.Documents.Open(ref filename, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing, ref Nothing);
 
//啟動強制保護
WordDoc.Protect((Word.WdProtectionType)ProtectLevel, Type.Missing, ProtectPassword);
 
//停止保護
 
WordDoc.Unprotect(ProtectPassword);

ArrayList ranges = new ArrayList();  //備份Range對象
ArrayList rangetexts = new ArrayList(); //備份Range對象的文本內容
//遍歷內容控件
foreach (Word.ContentControl cc in WordDoc.ContentControls)
{
//判斷格式文本內容控件，并判斷自定義屬性
   if (cc.Type == Word.WdContentControlType.wdContentControlText && (cc.Tag=="tag1"))
   {
       cc.MultiLine = true;             //允許多行內容
       cc.LockContentControl = false;   //解除鎖定內容
       cc.LockContents = false;         //解除鎖定控件
                       
       cc.Type = Word.WdContentControlType.wdContentControlRichText;  //設置富文本控件
       ranges.Add(cc.Range);              //添加range對象
       rangetexts.Add(cc.Range.Text);     //添加range對象的TEXT,在這里可以傳遞需要的值
       cc.LockContentControl = false;
       cc.Delete(true);     // 刪除控件
   }
}
 
int r = 0;
foreach(Word.Range ran in ranges)
{
   ran.Text = rangetexts[r].ToString();  //在控件的刪除點替換成需要的文本
   r++;
}

string DocVar_Value = "123";
//遍歷WORD變量
 foreach (Word.Variable ov in WordDoc.Variables)
 {
      if (ov.Name == "Sys_Custom_DocVar")  //判斷變量名稱，假設為 Sys_Custom_DocVar
      {
          // ov.Value  可訪問的值
          ov.Delete();   //找到要設置的變量，刪除
      }
 }
//添加WORD變量
 WordDoc.Variables.Add("Sys_Custom_DocVar", DocVar_Value);